Molecular characterization of blaVIM-2-carrying Pseudomonas asiatica L2126: identification of a ∼44 kb untypable plasmid with intra-genus dissemination potential
Our findings demonstrate that the carriage of bla<sub>VIM-2</sub> on a novel ∼44 kb untypable plasmid in P. asiatica L2126 could facilitate horizontal gene transfer of carbapenem resistance. The plasmid's high homology to one previously identified in P. monteilii suggests that it has the potential for intra-genus dissemination, posing a significant threat to the spread of carbapenem resistance.
Authors
- Lei Fang (ORCID: https://orcid.org/0000-0002-2582-4845)
- Ruishan Liu (ORCID: https://orcid.org/0000-0002-7298-0701)
- Yi Liu (ORCID: https://orcid.org/0000-0002-3710-2073)
- Jinhua Zhang (ORCID: https://orcid.org/0000-0001-7212-3227)
- Hao Xu (ORCID: https://orcid.org/0000-0002-8992-6488)
- Xinrui Wang (ORCID: https://orcid.org/0009-0006-1733-3831)
Institutions
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Hangzhou Red Cross Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Ministry of Public Health (MG)
- State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
- China Agricultural University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.jgar.2025.09.012
- Primary Topic
- Plant Pathogenic Bacteria Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00