Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE and Monitoring with Somatostatin Receptor PET/CT in Patients with Advanced Differentiated Thyroid Carcinoma

In advanced radioiodine-refractory DTC, PRRT may be beneficial even after treatment interruptions, without major side effects. Given the small cohort and retrospective design, further prospective studies are needed to optimize PRRT strategies in DTC, in particular in a rechallenge scenario.

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Publication Details

Journal
Molecular Imaging and Biology
Published
2025-09-29
DOI
https://doi.org/10.1007/s11307-025-02053-w
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE and Monitoring with Somatostatin Receptor PET/CT in Patients with Advanced Differentiated Thyroid Carcinoma

Vera Wenter, Rudolf Alexander Werner, Ralf Schirrmacher, Adrien Holzgreve et al.
Molecular Imaging and Biology
Thyroid Cancer Diagnosis and Treatment
article

Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE and Monitoring with Somatostatin Receptor PET/CT in Patients with Advanced Differentiated Thyroid Carcinoma

Vera Wenter, Rudolf Alexander Werner, Ralf Schirrmacher, Adrien Holzgreve, Gabriel T. Sheikh, Christine Spitzweg, Liam Widjaja, Simon Lindner, Franz Josef Gildehaus, Mathias J. Zacherl, Sophie C. Kunte, Christoph J. Auernhammer
article en

Abstract

In advanced radioiodine-refractory DTC, PRRT may be beneficial even after treatment interruptions, without major side effects. Given the small cohort and retrospective design, further prospective studies are needed to optimize PRRT strategies in DTC, in particular in a rechallenge scenario.

Molecular Imaging and BiologyVol. 27(6)
Johns Hopkins University (US), University of Alberta (CA), German Cancer Research Center (DE), Johns Hopkins Medicine (US), LMU Klinikum (DE), Bayerisches Landesamt für Umwelt (DE), Bavarian Broadcasting (DE), Mayo Clinic in Florida (US), Molecular Theranostics (United States) (US), Ludwig-Maximilians-Universität München (DE)
Deutsche Forschungsgemeinschaft
Openalex Percentile: Top 64%
Thyroid Cancer Diagnosis and Treatment
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