Analysis of Complications of Transbronchial Lung Cryobiopsy in Patients with Disseminated Lung Diseases

The objective: to study the frequency and spectrum of complications after transbronchial lung cryobiopsy. Subjects and Methods. A continuous retrospective study was conducted, which included 138 patients with pulmonary tissue dissemination syndrome. All those patients were treated in Novosibirsk Tuberculosis Research Institute from January 2023 to December 2024. To verify the diagnosis, all patients underwent transbronchial lung cryobiopsy. The authors assessed the diagnostic effectiveness of biopsy and complications that developed. Results. Transbronchial lung cryobiopsy allowed to verify the diagnosis in 109 (78.9%) of 138 patients. Complications were registered in 125 (90.6%) patients: bleeding – in 89.1%, grade 3 bleeding – in 3.6%, and pneumothorax – in 2.2%. There were no lethal outcomes.