SUZ12 knockdown restrains the proliferation, migration, and invasion of oral tongue squamous cell carcinoma through inhibiting DNMT1-mediated ZNF582 promoter methylation
SUZ12 knockdown inhibits the proliferation, migration, invasion and EMT in OTSCC cells by inhibiting DNMT1-mediated ZNF582 promoter methylation, thereby suppressing tumor growth in vivo.
Authors
- Zhihao Wu (ORCID: https://orcid.org/0000-0002-5406-9682)
- Chenchen Wang (ORCID: https://orcid.org/0000-0001-9386-2555)
- Yicheng Cheng (ORCID: https://orcid.org/0000-0001-7894-9759)
- Lin Zhang (ORCID: https://orcid.org/0000-0003-0018-3903)
- Xiangwei Kong (ORCID: https://orcid.org/0000-0003-1835-7596)
- Wei Hsian Yin
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12957-025-04015-6
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00