Beyond the Usual Barriers—A Primary Testicular Seminoma Arising in an Undescended Testis Presenting as a Colon Mass: A Case Report

Germ cell tumors (GCT) in men usually arise in the gonads, presenting as a testicular mass. GCT may rarely involve the gastrointestinal tract due to metastasis from the testicular tumor. GCT arising from an undescended testis and presenting primarily with gastrointestinal symptoms is extremely rare. We hereby present a primary testicular seminoma in a 51-year-old gentleman, presenting with gastrointestinal symptoms. Sigmoidoscopy showed a large ulcero-infiltrative growth (7 × 6 × 3 cm) in the cecum and proximal ascending colon. The growth was biopsied with a clinical suspicion of a primary colonic adenocarcinoma. The biopsy showed infiltration by a seminoma. A thorough clinicoradiological evaluation revealed right cryptorchidism in the patient. He later underwent right hemicolectomy which revealed an adherent remnant cryptorchid testis at ileocecal junction and colonic infiltration by seminoma. Though challenging to diagnose seminoma at an unusual site, accurate biopsy diagnosis can play a decisive role in planning the timely surgery and adjuvant chemotherapeutic options.

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Publication Details

Journal
International Journal of Surgical Pathology
Published
2025-09-29
DOI
https://doi.org/10.1177/10668969251377798
Primary Topic
Testicular diseases and treatments
Type
article
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article

Beyond the Usual Barriers—A Primary Testicular Seminoma Arising in an Undescended Testis Presenting as a Colon Mass: A Case Report

Shilpi Thakur, Puja Sakhuja, Sanjeev Sachdeva, Venkatesh Vaithiyam et al.
International Journal of Surgical Pathology
Testicular diseases and treatments
article

Beyond the Usual Barriers—A Primary Testicular Seminoma Arising in an Undescended Testis Presenting as a Colon Mass: A Case Report

Shilpi Thakur, Puja Sakhuja, Sanjeev Sachdeva, Venkatesh Vaithiyam, Surbhi Goyal, Krishna Bhardwaj, BG Vageesh, Savita Arora
article en

Abstract

Germ cell tumors (GCT) in men usually arise in the gonads, presenting as a testicular mass. GCT may rarely involve the gastrointestinal tract due to metastasis from the testicular tumor. GCT arising from an undescended testis and presenting primarily with gastrointestinal symptoms is extremely rare. We hereby present a primary testicular seminoma in a 51-year-old gentleman, presenting with gastrointestinal symptoms. Sigmoidoscopy showed a large ulcero-infiltrative growth (7 × 6 × 3 cm) in the cecum and proximal ascending colon. The growth was biopsied with a clinical suspicion of a primary colonic adenocarcinoma. The biopsy showed infiltration by a seminoma. A thorough clinicoradiological evaluation revealed right cryptorchidism in the patient. He later underwent right hemicolectomy which revealed an adherent remnant cryptorchid testis at ileocecal junction and colonic infiltration by seminoma. Though challenging to diagnose seminoma at an unusual site, accurate biopsy diagnosis can play a decisive role in planning the timely surgery and adjuvant chemotherapeutic options.

International Journal of Surgical PathologyVol. 34(2)
Govind Ballabh Pant Hospital (IN)
Openalex Percentile: Top 58%
Testicular diseases and treatments
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