Development and Validation of the PREVES-HOR Questionnaire: A Patient-Reported Measure of Hormone Therapy-Related Quality of Life in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy
Phase 1 findings support PREVES-HOR's content validity, internal coherence, and ability to detect clinically meaningful distress overlooked by broader instruments such as EPIC or FACT-P. Its forced-choice format eliminated missing data but will be reconsidered, along with responsiveness, test-retest stability, and cross-cultural adaptation, in the ongoing 1,000 patient phase 2/3 program. Pending confirmation, PREVES-HOR, may become a complementary tool for individualizing supportive care and evaluating ADT-modifying interventions.
Authors
- Emmanoel Vilaça Costa (ORCID: https://orcid.org/0000-0002-0153-822X)
- Raffaele Baio (ORCID: https://orcid.org/0000-0002-3157-0845)
- Matteo Ferro (ORCID: https://orcid.org/0000-0002-9250-7858)
- Carlo Buonerba (ORCID: https://orcid.org/0000-0002-1806-442X)
- Sisto Perdonà (ORCID: https://orcid.org/0000-0001-8683-4644)
- Armando Calogero (ORCID: https://orcid.org/0000-0003-2315-0610)
- Paolo Verze (ORCID: https://orcid.org/0000-0002-3789-8227)
- Francesco Maiorino
- Felice Crocetto (ORCID: https://orcid.org/0000-0002-4315-7660)
- Sabrina Rossetti (ORCID: https://orcid.org/0000-0002-9337-5885)
- Raffaele Balsamo (ORCID: https://orcid.org/0000-0002-9600-2179)
- Antonio Verde
- Giuseppe Di Lorenzo (ORCID: https://orcid.org/0000-0001-7414-1568)
- Annamaria Donnarumma
- Armando Ferraioli
- Oriana Strianese
- Rocco Papalia
- Pierluigi Bove (ORCID: https://orcid.org/0000-0002-4788-2982)
- Francesco Grillone (ORCID: https://orcid.org/0009-0009-6010-7604)
- Dario Bruzzese (ORCID: https://orcid.org/0000-0001-9911-4646)
- Francesco Prata (ORCID: https://orcid.org/0000-0003-3084-6210)
- Alfredo Tartarone (ORCID: https://orcid.org/0000-0002-0859-7847)
- Francesco Passaro
- Francesca Cappuccio
- Luca Scafuri (ORCID: https://orcid.org/0000-0002-7410-8300)
- Vittorino Montanaro
- Giuseppe Romeo
- Antonio Aliberti
- Antonio Ruffo
- Vittorio Riccio
- Eleonora Monteleone
- Concetta Scocca
- Giacomo Metta
Institutions
- University of Rome Tor Vergata (IT)
- University of Molise (IT)
- University of Salerno (IT)
- Università Campus Bio-Medico (IT)
- University of Milan (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Regione Campania (IT)
- Ospedale Antonio Cardarelli (IT)
- Centro di Riferimento Oncologico della Basilicata (IT)
- Saint Camillus International University of Health and Medical Sciences (IT)
- Ospedale San Paolo (IT)
- Ospedale Santa Maria (IT)
- CTO Andrea Alesini (IT)
- Federico II University Hospital (IT)
- Istituto di Ematologia di Bologna (IT)
- Newcastle upon Tyne Hospital (GB)
- Azienda Ospedaliero-Universitaria "Renato Dulbecco" (IT)
- Policlinico Tor Vergata (IT)
- Ospedale Monaldi (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Campus Bio Medico University Hospital (IT)
- Ospedale Sant'Anna (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Oncology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1159/000548317
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 0.00