When MOGAD mimics MS: diagnostic and therapeutic insights from a unique CNS demyelinating case

This case reveals that varied MRI features in MOGAD underscore the complexity of the disease. Although OCB positivity is associated with a higher risk of relapse in MOGAD patients [1-3]continuous MRI remains the primary method for detecting subclinical disease activity. Due to its invasive nature and limited value in assessing disease progression, repeated CSF analysis for routine OCB monitoring is not recommended.

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Publication Details

Journal
BMC Neurology
Published
2025-09-29
DOI
https://doi.org/10.1186/s12883-025-04442-8
Primary Topic
Multiple Sclerosis Research Studies
Type
article
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article

When MOGAD mimics MS: diagnostic and therapeutic insights from a unique CNS demyelinating case

Lin Chen, Ya Chen, Ziyi Xu, Ping Xu et al.
BMC Neurology
Multiple Sclerosis Research Studies
article

When MOGAD mimics MS: diagnostic and therapeutic insights from a unique CNS demyelinating case

Lin Chen, Ya Chen, Ziyi Xu, Ping Xu, Ya Luo
article en

Abstract

This case reveals that varied MRI features in MOGAD underscore the complexity of the disease. Although OCB positivity is associated with a higher risk of relapse in MOGAD patients [1-3]continuous MRI remains the primary method for detecting subclinical disease activity. Due to its invasive nature and limited value in assessing disease progression, repeated CSF analysis for routine OCB monitoring is not recommended.

BMC NeurologyVol. 25(1)
Zunyi Medical University (CN)
Openalex Percentile: Top 62%
Multiple Sclerosis Research Studies
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