Risk of HBV transmission from HBcAb-positive grafts in pediatric liver transplantation: a real-world prospective cohort study
HBcAb-positive grafts substantially increase HBV transmission risk in pediatric liver transplantation. Elevated HBsAb titers may mitigate infection severity, while occult HBV infections require vigilant monitoring. Strategic enhancement of recipient HBsAb levels and optimized prophylactic protocols are critical for improving outcomes.
Authors
- Mingman Zhang
- Yao Zhao (ORCID: https://orcid.org/0000-0003-4550-9436)
- Yue Lu (ORCID: https://orcid.org/0000-0003-0466-9257)
- Yuting Yang (ORCID: https://orcid.org/0000-0002-6411-5937)
- Kenneth Boon Kiat Tan (ORCID: https://orcid.org/0000-0003-2167-690X)
- Xiaoke Dai
- Guojin Wu
- Tengteng Zhang (ORCID: https://orcid.org/0009-0006-6686-2027)
Institutions
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12985-025-02941-1
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing Medical University
- Natural Science Foundation of Chongqing
- Centre Scientifique et Technique du Bâtiment