American College of Radiology–Developed Thyroid Imaging Reporting and Data System 3, 4, and 5 thyroid nodules are distinctive by cytology, genetic imprints, and histology
TI-RADS 3, 4, and 5 nodules demonstrate distinct cytologic, molecular, and histologic features. TI-RADS 3 and 4 nodules are associated with lower malignancy risks, whereas TI-RADS 5 nodules exhibit a high risk of malignancy and are associated with higher mortality.
Authors
- Adebowale Adeniran (ORCID: https://orcid.org/0000-0001-9820-632X)
- Sanhong Yu
- Guoping Cai (ORCID: https://orcid.org/0000-0002-8725-5940)
- Minhua Wang (ORCID: https://orcid.org/0000-0002-2283-7050)
- Sara I. Pai (ORCID: https://orcid.org/0000-0002-6341-9971)
- Manju L. Prasad (ORCID: https://orcid.org/0000-0002-4507-2601)
- Jessica Zhao (ORCID: https://orcid.org/0000-0003-1323-2030)
- John H. Sinard (ORCID: https://orcid.org/0000-0001-8739-517X)
- J Langdon
Institutions
- Yale University (US)
Publication Details
- Journal
- Cancer Cytopathology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1002/cncy.70050
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00