Glypican-3–Targeted PET Imaging for Precise Diagnosis of Hepatocellular Carcinoma: From Bench to Bedside
[68Ga]Ga-XH-06 is clinically promising for detecting GPC3-positive HCC with a favorable safety profile. Further investigation is warranted to validate the clinical value of GPC3-targeted PET imaging in HCC management. See related commentary by Seo and Flavell, p. 445.
Authors
- Jianwei Zhu (ORCID: https://orcid.org/0000-0001-6782-2023)
- Wenzhu Hu
- Zhaoguo Lin (ORCID: https://orcid.org/0000-0002-1545-9725)
- Dawei Jiang (ORCID: https://orcid.org/0000-0002-4072-0075)
- Mengting Li (ORCID: https://orcid.org/0000-0002-0715-0015)
- Zhangyi Song (ORCID: https://orcid.org/0000-0003-0577-0664)
- Xiaoying Lv
- Yongkang Gai (ORCID: https://orcid.org/0000-0001-6766-5240)
- Xiangming Song (ORCID: https://orcid.org/0000-0001-8990-3561)
- Shusheng Wang
- Zhidi Pan (ORCID: https://orcid.org/0000-0002-6253-8522)
- Danzha Zheng
- Xiaoli Lan (ORCID: https://orcid.org/0000-0002-7263-7399)
- Xiao Zhang (ORCID: https://orcid.org/0000-0002-7305-5278)
- Yuan Feng (ORCID: https://orcid.org/0009-0002-2796-5761)
- Xiong Cai (ORCID: https://orcid.org/0000-0003-2034-9130)
- Ming Yang
- Haiyang Yin
- Wansheng Ruan
Institutions
- Shanghai Jiao Tong University (CN)
- Wuhan University (CN)
- Sino Biopharmaceutical (China) (CN)
- Shanghai FRP Research Institute (China) (CN)
- Ministry of Education (CL)
- Shanghai Institute of Applied Physics (CN)
- Western Laboratories (United States) (US)
- Wuhan Union Hospital (CN)
- BioScience Laboratories (United States) (US)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-1856
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06