CCR4⁺ memory Tregs and PD-1⁺ T cells as novel immunodiagnostic biomarkers for active tuberculosis
Differentiation and function of T cell subset are associated with TB infection. CCR4⁺ memory Tregs, CD4<sup>+</sup>PD-1<sup>+</sup> T cells, and CD8<sup>+</sup>PD-1<sup>+</sup> T cells show potential predictive value for ATB.
Authors
- Zheyue Wang
- Feifei Hu
- Fengyu Tian
- Xiaowei Deng (ORCID: https://orcid.org/0000-0001-7634-5257)
- Zhenpeng Guo
- Huakai Hu (ORCID: https://orcid.org/0009-0001-4344-8337)
- Yifan Zhang (ORCID: https://orcid.org/0009-0003-9724-6874)
- Qiang Zhang (ORCID: https://orcid.org/0000-0002-5923-2696)
- Jianming Wang (ORCID: https://orcid.org/0000-0002-9151-284X)
- S. Song
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- Ministry of Education (KR)
- Changzhou Third People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1186/s12879-025-11623-w
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province