Giant Vein of Galen Malformation as a Cause of TIA- A Case Report

Introduction: Vein of Galen malformations (VOGMs) are rare vascular entities originating from persistent shunting of primitive choroidal vessels into the median prosencephalic vein of Markowski. They usually present in infancy or childhood as seizures, hydrocephalus or cardiac failure; adult presentations are uncommon. In addition, giant VOGM in an adult is extremely rare to find. Case description: We present an exceedingly rare case of a giant VOGM measuring 3.4 x 3.7 x 3.2 cm in a 20-year-old female presenting as episodes of transient ischemic attack (TIA) which was obliterated successfully using endovascular embolization. Conclusion: VOGMs are associated with poor clinical outcome if left untreated. With advancement in endovascular techniques of obliteration, proper timely management can lead to good outcomes.

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Journal
Nepal Journal of Neuroscience
Published
2025-09-29
DOI
https://doi.org/10.3126/njn.v22i2.63512
Primary Topic
Vascular Malformations Diagnosis and Treatment
Type
article
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article

Giant Vein of Galen Malformation as a Cause of TIA- A Case Report

Chayanika Kutum, Mahesh Mahajan, Prashant Lakhe, Daljit Singh
Nepal Journal of Neuroscience
Vascular Malformations Diagnosis and Treatment
article

Giant Vein of Galen Malformation as a Cause of TIA- A Case Report

Chayanika Kutum, Mahesh Mahajan, Prashant Lakhe, Daljit Singh
article en

Abstract

Introduction: Vein of Galen malformations (VOGMs) are rare vascular entities originating from persistent shunting of primitive choroidal vessels into the median prosencephalic vein of Markowski. They usually present in infancy or childhood as seizures, hydrocephalus or cardiac failure; adult presentations are uncommon. In addition, giant VOGM in an adult is extremely rare to find. Case description: We present an exceedingly rare case of a giant VOGM measuring 3.4 x 3.7 x 3.2 cm in a 20-year-old female presenting as episodes of transient ischemic attack (TIA) which was obliterated successfully using endovascular embolization. Conclusion: VOGMs are associated with poor clinical outcome if left untreated. With advancement in endovascular techniques of obliteration, proper timely management can lead to good outcomes.

Nepal Journal of NeuroscienceVol. 22(2)
Mahatma Gandhi Memorial Medical College (IN), Govind Ballabh Pant Hospital (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 62%
Vascular Malformations Diagnosis and Treatment
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Giant Vein of Galen Malformation as a Cause of TIA- A Case Report — Chayanika Kutum, Mahesh Mahajan, et al. · Nepal Journal of Neuroscience (2025) | TGRS Research Map | TGRS