New sex hormone-binding globulin and estimated free testosterone reference intervals for children and adolescents: The effects of age, sex, BMI and oral contraceptives

We present SHBG percentiles for children and adolescents to support diagnoses of sex-hormone-related diseases. Confounders, such as BMI, Tanner stages, and contraceptive use should also be considered when interpreting SHBG measurements. Trial registration number - NCT02550236.

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Publication Details

Journal
Clinica Chimica Acta
Published
2025-09-26
DOI
https://doi.org/10.1016/j.cca.2025.120621
Primary Topic
Hormonal and reproductive studies
Type
article
Field-Weighted Citation Impact
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article

New sex hormone-binding globulin and estimated free testosterone reference intervals for children and adolescents: The effects of age, sex, BMI and oral contraceptives

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New sex hormone-binding globulin and estimated free testosterone reference intervals for children and adolescents: The effects of age, sex, BMI and oral contraceptives

Uta Ceglarek, Wieland Kieß, Mandy Vogel, Jürgen Kratzsch, Philip Johann Wölfle, Pierre Dürgen
article en

Abstract

We present SHBG percentiles for children and adolescents to support diagnoses of sex-hormone-related diseases. Confounders, such as BMI, Tanner stages, and contraceptive use should also be considered when interpreting SHBG measurements. Trial registration number - NCT02550236.

Clinica Chimica ActaVol. 579
University Hospital Leipzig (DE), Leipzig University (DE)
Openalex Percentile: Top 64%
Hormonal and reproductive studies
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