Hemichorea caused by polycythemia vera

Polycythaemia vera (PV) is a chronic myeloproliferative disorder. PV should be suspected with hemoglobin >10.2/9.9 mmol/L (m/f) and/or PV-related features (aquagenic pruritus, erythromelalgia, atypical thrombosis, splenomegaly, thrombocytosis or leukocytosis). This case report highlights the connection between PV and neurological manifestations, including rare symptoms like chorea. An 82-year-old woman presented with sudden choreiform movements, dysarthria, and behavioral changes. Investigations ruled out primary neurological disease and confirmed PV. With treatment, the neurological symptoms resolved.

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Publication Details

Journal
Ugeskrift for Læger
Published
2025-09-22
DOI
https://doi.org/10.61409/v04250261
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
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article

Hemichorea caused by polycythemia vera

Peter Buur van Kooten Niekerk, Peter Kolind Brask‐Thomsen, Nanna Wittrup Sodemann
Ugeskrift for Læger
Hemoglobinopathies and Related Disorders
article

Hemichorea caused by polycythemia vera

Peter Buur van Kooten Niekerk, Peter Kolind Brask‐Thomsen, Nanna Wittrup Sodemann
article en

Abstract

Polycythaemia vera (PV) is a chronic myeloproliferative disorder. PV should be suspected with hemoglobin >10.2/9.9 mmol/L (m/f) and/or PV-related features (aquagenic pruritus, erythromelalgia, atypical thrombosis, splenomegaly, thrombocytosis or leukocytosis). This case report highlights the connection between PV and neurological manifestations, including rare symptoms like chorea. An 82-year-old woman presented with sudden choreiform movements, dysarthria, and behavioral changes. Investigations ruled out primary neurological disease and confirmed PV. With treatment, the neurological symptoms resolved.

Ugeskrift for LægerVol. 187(39)
Aarhus University Hospital (DK), Rigshospitalet (DK)
Openalex Percentile: Top 63%
Hemoglobinopathies and Related Disorders
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