Generation and Phenotypic Analysis of the <i>IL-10RA</i> <i>R104W/R104W</i> Mouse Model
In summary, we have successfully constructed a humanized mouse model with a stable spontaneous colitis phenotype, which is a valuable model for the therapeutic exploration of VEO-IBD.
Authors
- X. G. Cao (ORCID: https://orcid.org/0000-0003-2795-9601)
- Zhiyang Zeng (ORCID: https://orcid.org/0000-0002-0235-1352)
- Xiao-Ying Cao
- Yan He (ORCID: https://orcid.org/0000-0001-7928-2677)
- Xueli Zhang (ORCID: https://orcid.org/0000-0002-7741-1081)
- Dali Li (ORCID: https://orcid.org/0000-0002-0679-8477)
- Liren Wang (ORCID: https://orcid.org/0009-0009-8737-2408)
Institutions
- Xian Central Hospital (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- Shanghai Sixth People's Hospital (CN)
- East China Normal University (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1093/ibd/izaf099
- Citations
- 1
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.05