Rational Design of Betulin-Based Hybrids as Multi-Target Inhibitors of Anti-Apoptotic BCL Proteins

Triterpenes such as betulin are intensively studied for their intrinsic pro-apoptotic effects in cancer, providing a privileged scaffold for anti-tumor drug design [...]

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Published
2025-09-28
DOI
https://doi.org/10.3390/proceedings2025127021
Primary Topic
Natural product bioactivities and synthesis
Type
article
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article

Rational Design of Betulin-Based Hybrids as Multi-Target Inhibitors of Anti-Apoptotic BCL Proteins

Marius Mioc, Mihaela Čoban
Natural product bioactivities and synthesis
article

Rational Design of Betulin-Based Hybrids as Multi-Target Inhibitors of Anti-Apoptotic BCL Proteins

Marius Mioc, Mihaela Čoban
article en

Abstract

Triterpenes such as betulin are intensively studied for their intrinsic pro-apoptotic effects in cancer, providing a privileged scaffold for anti-tumor drug design [...]

Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
Openalex Percentile: Top 77%
Natural product bioactivities and synthesis
DOIOpen Access PDFOpenAlex
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Rational Design of Betulin-Based Hybrids as Multi-Target Inhibitors of Anti-Apoptotic BCL Proteins — Marius Mioc, Mihaela Čoban · (2025) | TGRS Research Map | TGRS