Cervical spinal inflammatory myofibroblastic tumour in a 3‐year‐old dog ( <i>Canis lupus familiaris</i> )

Abstract A 3‐year‐old, female, spayed cross‐breed dog presented with a history of progressive right‐sided hemiparesis and cervical hyperesthesia. The neurological examination results were consistent with a C1–C5 myelopathy. Magnetic resonance imaging revealed an extradural mass located along the vertebral body of C4 in a right lateral position, causing dislocation and compression of the spinal cord. The preliminary diagnosis was a neoplastic lesion. An infectious‐inflammatory lesion was considered to be a less likely differential diagnosis. A right‐lateralized dorsal laminectomy was performed, providing spinal cord and lesion visualization, which was subsequently excised. Histological and immunohistochemical examinations revealed an abnormal proliferation of spindle cells associated with marked multifocal lymphoplasmacytic infiltration, consistent with an inflammatory myofibroblastic tumour. Normal gait was restored within 3 months from surgery and the patient did not exhibit signs of pain in the subsequent months. Follow‐up magnetic resonance imaging did not show signs of recurrence of the lesion 1 year after surgery.

Authors

Institutions

Publication Details

Journal
Veterinary Record Case Reports
Published
2025-09-28
DOI
https://doi.org/10.1002/vrc2.70220
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Cervical spinal inflammatory myofibroblastic tumour in a 3‐year‐old dog ( Canis lupus familiaris )

Sara Canal, Carlo Cantile, Alberto Cauduro, G J Padovan et al.
Veterinary Record Case Reports
IgG4-Related and Inflammatory Diseases
article

Cervical spinal inflammatory myofibroblastic tumour in a 3‐year‐old dog ( Canis lupus familiaris )

Sara Canal, Carlo Cantile, Alberto Cauduro, G J Padovan, Andrea Di Paola
article en

Abstract

Abstract A 3‐year‐old, female, spayed cross‐breed dog presented with a history of progressive right‐sided hemiparesis and cervical hyperesthesia. The neurological examination results were consistent with a C1–C5 myelopathy. Magnetic resonance imaging revealed an extradural mass located along the vertebral body of C4 in a right lateral position, causing dislocation and compression of the spinal cord. The preliminary diagnosis was a neoplastic lesion. An infectious‐inflammatory lesion was considered to be a less likely differential diagnosis. A right‐lateralized dorsal laminectomy was performed, providing spinal cord and lesion visualization, which was subsequently excised. Histological and immunohistochemical examinations revealed an abnormal proliferation of spindle cells associated with marked multifocal lymphoplasmacytic infiltration, consistent with an inflammatory myofibroblastic tumour. Normal gait was restored within 3 months from surgery and the patient did not exhibit signs of pain in the subsequent months. Follow‐up magnetic resonance imaging did not show signs of recurrence of the lesion 1 year after surgery.

Veterinary Record Case ReportsVol. 13(4)
University of Pisa (IT), Pontifical Gregorian University (IT), University of Ferrara (IT), Centro Clinico Nemo (IT)
Openalex Percentile: Top 61%
IgG4-Related and Inflammatory Diseases
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.