Deoxycholic Acid Promotes Persistent Low‐Level Viremia in Chronic Hepatitis B via Enhancing HBV Particle Formation
Elevated DCA promotes viral persistence by enhancing Dane particle formation and stabilizing HBs-HBc interactions, contributing to LLV during treatment. Modulating BA metabolism may offer new strategies to improve CHB therapy.
Authors
- Pengxiang Yang (ORCID: https://orcid.org/0000-0003-2777-7533)
- Yuanyue Guan
- Dexi Chen (ORCID: https://orcid.org/0000-0002-6896-6640)
- Yuxue Gao (ORCID: https://orcid.org/0009-0002-0734-2583)
- Yuying Cai
- Qiqi Ning
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-09-28
- DOI
- https://doi.org/10.1111/jgh.70090
- Citations
- 2
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71