A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast

We present a rare case of squamous cell carcinoma arising from an intraductal papilloma in a 60-year-old female. Histopathology revealed an invasive squamous cell carcinoma with p63 positivity, coexisting with a benign papilloma. Following partial mastectomy and adjuvant therapy, the patient remained disease-free for 4 years and 8 months, highlighting the importance of early detection.

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Publication Details

Journal
Clinical Case Reports
Published
2025-09-28
DOI
https://doi.org/10.1002/ccr3.71068
Primary Topic
Cancer and Skin Lesions
Type
article
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article

A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast

Kumiko Okujima, Yosuke Mizuno, Kanako Nishiyama
Clinical Case Reports
Cancer and Skin Lesions
article

A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast

Kumiko Okujima, Yosuke Mizuno, Kanako Nishiyama
article en

Abstract

We present a rare case of squamous cell carcinoma arising from an intraductal papilloma in a 60-year-old female. Histopathology revealed an invasive squamous cell carcinoma with p63 positivity, coexisting with a benign papilloma. Following partial mastectomy and adjuvant therapy, the patient remained disease-free for 4 years and 8 months, highlighting the importance of early detection.

Clinical Case ReportsVol. 13(10)
Matsuyama Red Cross Hospital (JP)
Openalex Percentile: Top 53%
Cancer and Skin Lesions
DOIOpen Access PDFOpenAlex
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A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast — Kumiko Okujima, Yosuke Mizuno, et al. · Clinical Case Reports (2025) | TGRS Research Map | TGRS