Requiem for the Passing–Bablok nonparametric regression in assessing the agreement between two measurement methods

The Passing-Bablok 95 % CIs are too wide for being included in sensible agreement thresholds according to a population equivalence model and, finally, this approach cannot be considered under the best agreement model of the individual equivalence.

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Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2025-09-28
DOI
https://doi.org/10.1515/cclm-2025-0581
Primary Topic
Reliability and Agreement in Measurement
Type
article
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article

Requiem for the Passing–Bablok nonparametric regression in assessing the agreement between two measurement methods

Bruno Mario Cesana, Paolo Antonelli
Clinical Chemistry and Laboratory Medicine (CCLM)
Reliability and Agreement in Measurement
article

Requiem for the Passing–Bablok nonparametric regression in assessing the agreement between two measurement methods

Bruno Mario Cesana, Paolo Antonelli
article en

Abstract

The Passing-Bablok 95 % CIs are too wide for being included in sensible agreement thresholds according to a population equivalence model and, finally, this approach cannot be considered under the best agreement model of the individual equivalence.

Clinical Chemistry and Laboratory Medicine (CCLM)Vol. 64(2)
University of Milan (IT), University of Brescia (IT)
Openalex Percentile: Top 74%
Reliability and Agreement in Measurement
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