Diagnostic Utility of Antibodies to Extractable Nuclear Antigens in the Absence of Positive Antinuclear Antibodies
The utility of testing for ENA when the ANA by IFA is negative is low. The vast majority of positive tests are false positives that lead to additional testing at additional costs.
Authors
- Jason C. Huang (ORCID: https://orcid.org/0009-0008-9286-1786)
- Michael E. Luggen (ORCID: https://orcid.org/0000-0002-1945-0103)
- Bassel B Dargham
Institutions
- Cincinnati VA Medical Center (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-28
- DOI
- https://doi.org/10.7759/cureus.93419
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00