Application of Skin Protective Film Combined with Negative Pressure Regulation to Prevent Skin Injury After Chronic Wound VSD

<i>Objective:</i> To evaluate the efficacy of skin protective film combined with negative pressure adjustment in preventing periwound skin injury after vacuum sealing drainage (VSD) surgery for chronic wounds. <i>Methods:</i> From September 2022 to December 2023, 200 patients with chronic wounds undergoing VSD surgery were randomly divided into four groups (A, B, C, D) of 50 each. Group A used low negative pressure (-120 to -70 mmHg), Group B used traditional negative pressure (-450 to -125 mmHg), Group C combined skin protective film with low negative pressure, and Group D combined skin protective film with traditional negative pressure. Outcomes included skin injury incidence, granulation tissue growth, and pain and comfort scores on postoperative days 1, 3, and 5. <i>Results:</i> Group C showed a significantly lower skin injury rate (12.2%) than Group B (37.5%) (P<0.008). No significant differences were found in granulation tissue growth among the groups (P>0.05). Pain scores were significantly lower in low negative pressure groups (A and C) on postoperative days 1 and 3 (P<0.05), with no differences on day 5 (P>0.05). Comfort scores were significantly higher in skin protective film groups (C and D) on postoperative day 5 (P<0.05). <i>Conclusion:</i> Skin protective film combined with low negative pressure effectively reduces skin injury incidence, alleviates early postoperative pain, and enhances late postoperative comfort, offering practical clinical benefits.