Use of Autologous hematopoietic stem cell transplantation for a patient with primary nasal NK/T-cell lymphoma combined with hemophagocytic syndrome

Extranodal NK/T-cell lymphoma, nasal type (ENKTCL-NT) is a type of primary nasal peripheral T-cell lymphoma, which is a rare type of non-Hodgkin's lymphoma, especially with hemophagocytic syndrome (HPS), and can easily lead to clinical misdiagnosis. The disease is dangerous, it progresses rapidly, and the treatment is ineffective. This article reports a case of ENKTCL-NT with HPS, which involves the primary nasal cavity invading the oral cavity. Patients attain improved remission outcomes with autologous hematopoietic stem cell transplantation (ASCT) in combination with chemotherapy. This paper reviews current domestic and international research and summarizes diagnostic and therapeutic approaches to enhance clinicians' comprehension of the disease.

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Publication Details

Journal
Head and Neck Diseases Conflux
Published
2025-08-10
DOI
https://doi.org/10.71321/sx17sm66
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Use of Autologous hematopoietic stem cell transplantation for a patient with primary nasal NK/T-cell lymphoma combined with hemophagocytic syndrome

Hongfeng Ge, Weixia Wu, Siqi Zhang, Xiaoxing Sun et al.
Head and Neck Diseases Conflux
Autoimmune and Inflammatory Disorders Research
article

Use of Autologous hematopoietic stem cell transplantation for a patient with primary nasal NK/T-cell lymphoma combined with hemophagocytic syndrome

Hongfeng Ge, Weixia Wu, Siqi Zhang, Xiaoxing Sun, Yanrong Zhang, Miao Xing, Chun‐Bo Feng
article en

Abstract

Extranodal NK/T-cell lymphoma, nasal type (ENKTCL-NT) is a type of primary nasal peripheral T-cell lymphoma, which is a rare type of non-Hodgkin's lymphoma, especially with hemophagocytic syndrome (HPS), and can easily lead to clinical misdiagnosis. The disease is dangerous, it progresses rapidly, and the treatment is ineffective. This article reports a case of ENKTCL-NT with HPS, which involves the primary nasal cavity invading the oral cavity. Patients attain improved remission outcomes with autologous hematopoietic stem cell transplantation (ASCT) in combination with chemotherapy. This paper reviews current domestic and international research and summarizes diagnostic and therapeutic approaches to enhance clinicians' comprehension of the disease.

Head and Neck Diseases ConfluxVol. 1(1)
Bozhou People's Hospital (CN)
Anhui Medical University
Openalex Percentile: Top 65%
Autoimmune and Inflammatory Disorders Research
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Use of Autologous hematopoietic stem cell transplantation for a patient with primary nasal NK/T-cell lymphoma combined with hemophagocytic syndrome — Hongfeng Ge, Weixia Wu, et al. · Head and Neck Diseases Conflux (2025) | TGRS Research Map | TGRS