Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial

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Publication Details

Journal
Drugs
Published
2025-09-28
DOI
https://doi.org/10.1007/s40265-025-02250-5
Citations
5
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
4.21

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article

Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial

John A. Hey, Emer MacSweeney, Adem Albayrak, Anton P. Porsteinsson et al.
5 citations
Drugs
Neurological Disease Mechanisms and Treatments
4.21
article

Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial

John A. Hey, Emer MacSweeney, Adem Albayrak, Anton P. Porsteinsson, Susan Flint, Yongxin Yu, Merçé Boada, Jean F. Schaefer, David Watson, Martin Tolar, Marwan Sabbagh, Rosalind McLaine, Sharon Cohen, J. Patrick Kesslak, Aidan Power, Sam Dickson, P. Murali Doraiswamy, Earvin Liang, Susan Abushakra, Luke Tolar
article en
5 citations

Abstract

No abstract available for this paper.
DrugsVol. 85(11)
Barrow Neurological Institute (US), Duke University (US), Universitat Internacional de Catalunya (ES), Alzheimer’s Disease Neuroimaging Initiative (US), TetraLogic Pharmaceuticals (United States) (US), Framingham State University (US), University of Rochester (US)
Göteborgs Universitet, National Institute on Aging
Openalex Percentile: Top 5%
Neurological Disease Mechanisms and Treatments
4.21
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