MALT–LYMPHOMAS IN PRIMARY SJÖGREN'S SYNDROME

Sjögren's syndrome is a systemic autoimmune disease involving the exocrine glands. In the course of the disease, in parallel with the systemic manifestations, lymphoproliferative disorders frequently. The risk of developing lymphomas in patients with Sjögren's syndrome is increased up to 44 times compared to the rest of the population. Among them, MALT-lymphomas, which have an indolent course, occupy a special place. Genetic factors, immune processes and chronic inflammation play a role in the basis of the malignant transformation of the disease, especially the site of infection with Helicobacter pylori.