Efficacy and safety of lemborexant in patients with insomnia: a systematic review and meta-analysis
Lemborexant demonstrates significant efficacy in improving sleep parameters in patients with insomnia and has a generally favorable safety profile. These findings support its role as an effective pharmacological option. Further high-quality studies are needed to confirm its efficacy and safety.
Authors
- Uazman Alam (ORCID: https://orcid.org/0000-0002-3190-1122)
- Hammad Javaid (ORCID: https://orcid.org/0009-0002-8938-0435)
- Umair Hayat (ORCID: https://orcid.org/0000-0001-5346-3891)
- Hamza Khan (ORCID: https://orcid.org/0000-0001-7024-974X)
- Muhammad Abdullah Ali (ORCID: https://orcid.org/0009-0002-3199-7862)
- Abdul Qadeer (ORCID: https://orcid.org/0009-0008-2211-200X)
- Allahdad Khan (ORCID: https://orcid.org/0009-0006-2003-922X)
- Shree Rath (ORCID: https://orcid.org/0009-0000-4273-0827)
- Cynthia Ward
- Raheel Ahmed
- Asad Ali Ahmed Cheema (ORCID: https://orcid.org/0009-0004-4664-591X)
- Zaryab Bacha (ORCID: https://orcid.org/0009-0008-6821-5653)
Institutions
- King Edward Medical University (PK)
- Khyber Medical College (PK)
- Nishtar Medical College and Hospital (PK)
- Khyber Medical University (PK)
- Lady Reading Hospital (PK)
- Lung Institute (US)
- All India Institute of Medical Sciences Bhubaneswar (IN)
- Sunderland Royal Hospital (GB)
- Mayo Clinic Hospital (US)
- International University of Kyrgyzstan (KG)
Publication Details
- Journal
- Sleep Medicine
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1016/j.sleep.2025.106823
- Citations
- 2
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.24