Protective Effects of Coixol Against Nε-Carboxymethyllysine-Induced Injury in IMR-32 Neuronal Cells: Modulation of Endoplasmic Reticulum Stress and Amyloidogenic Pathways
Compared to NALC and 4-PBA, coixol demonstrated comparable or superior modulation across multiple pathological pathways. These findings highlight coixol's potential as a neuroprotective candidate in AGE-associated neurodegenerative conditions.
Authors
- I-Min Liu (ORCID: https://orcid.org/0000-0001-5399-8853)
- Mei-Chou Lai
- Wayne Young Liu
- Yew‐Min Tzeng (ORCID: https://orcid.org/0000-0002-9360-2072)
Institutions
- Kaohsiung Medical University (TW)
- Jen-Ai Hospital (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Tajen University (TW)
- Central Taiwan University of Science and Technology (TW)
Publication Details
- Journal
- Nutrients
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3390/nu17182939
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Science and Technology, Taiwan