The mechanism of SMAD4/ERK pathway in regulating Th17/Treg cell differentiation leading to olfactory dysfunction in chronic rhinosinusitis
The deletion of SMAD4 regulates the differentiation of Th17/Treg cells via ERK1/2 phosphorylation, thereby exacerbating the olfactory dysfunction of CRS.
Authors
- Ning Wen (ORCID: https://orcid.org/0000-0001-9776-8056)
- Rui Chen
- Jinmei Ning
- Shouming Cao
- Haiying Wu (ORCID: https://orcid.org/0000-0002-8943-5267)
- Yan Niu
Institutions
- Kunming Medical University (CN)
- Qujing Normal University (CN)
Publication Details
- Journal
- Molecular Immunology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1016/j.molimm.2025.09.006
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00