Preferences for clinical trial participation among people who use drugs in rural Oregon and Appalachian Ohio
Rural PWUD preferences underscore the need to redesign clinical trial protocols with equity and feasibility at the forefront. Direct transportation support emerged as the top priority, reflecting how rural poverty and isolation limit access. Preferences for shorter and later-day appointments suggest a need for low-burden, flexible scheduling. Incorporating participant-centered features can improve trust, enrollment, and retention, ensuring rural PWUD are included in research that addresses their needs.
Authors
- Sarann Bielavitz (ORCID: https://orcid.org/0000-0003-2104-6991)
- Ryan Cook (ORCID: https://orcid.org/0000-0001-8754-995X)
- Caroline Koudelka
- Kathryn Elizabeth Lancaster (ORCID: https://orcid.org/0000-0003-2389-6973)
- P. Todd Korthuis (ORCID: https://orcid.org/0000-0001-5556-3597)
- Miriam Elman (ORCID: https://orcid.org/0000-0003-3162-6500)
- Angela T. Estadt (ORCID: https://orcid.org/0000-0002-2951-051X)
- April M. Young (ORCID: https://orcid.org/0000-0003-3969-3249)
- Madison N. Enderle (ORCID: https://orcid.org/0000-0002-2592-0781)
Institutions
- University of Kentucky (US)
- Oregon Health & Science University (US)
- Wake Forest University (US)
- The Ohio State University (US)
Publication Details
- Journal
- Drug and Alcohol Dependence
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.drugalcdep.2025.112894
- Citations
- 1
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 1.88