Changes in intestinal microbiota in pediatric cystic fibrosis patients after 6 months of elexacaftor‐tezacaftor‐ivacaftor therapy
ELX/TEZ/IVA therapy for 6 months induces changes in the intestinal microbiota composition of pediatric patients with CF, characterized by a reduction in potentially harmful bacteria and an increase in potentially beneficial bacteria. These findings suggest a modulation towards a healthier intestinal microbiota profile.
Authors
- C. Quirós (ORCID: https://orcid.org/0000-0002-9805-4044)
- Carmen Martin‐Fernández (ORCID: https://orcid.org/0000-0003-0843-2580)
- David González Jiménez (ORCID: https://orcid.org/0000-0001-8696-9194)
- José Ramón Gutiérrez Martínez (ORCID: https://orcid.org/0000-0001-6724-6636)
- Ruth García‐Romero
- Saioa Vicente‐Santamaría (ORCID: https://orcid.org/0000-0003-2082-8983)
- Juan José Díaz (ORCID: https://orcid.org/0000-0003-0962-8403)
- Isabel Gutiérrez‐Díaz (ORCID: https://orcid.org/0000-0003-0388-8431)
- Natalia Bastón-Paz
- Agustín De la Mano-Hernández
- Encarnación Torcuato‐Rubio
- Susana Delgado‐Palacios
Institutions
- Instituto Cajal (ES)
- Instituto de Productos Lácteos de Asturias (ES)
- Hospital Regional Universitario de Málaga (ES)
- Hospital Infantil Universitario Niño Jesús (ES)
- Hospital Universitario Miguel Servet (ES)
- Hospital Materno-Infantil (ES)
- Hospital Universitario Central de Asturias (ES)
- Hospital Universitario Ramón y Cajal (ES)
- Instituto de Investigación Sanitaria del Principado de Asturias (ES)
Publication Details
- Journal
- Journal of Pediatric Gastroenterology and Nutrition
- Published
- 2025-09-28
- DOI
- https://doi.org/10.1002/jpn3.70216
- Citations
- 2
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 3.04