Cellular Aging: Mechanisms and Interventions

Aging is a complex process that happens in our bodies, especially inside our cells, increasing vulnerability to diseases and death.The importance of studying aging lies in its direct association with major age-related diseases such as Alzheimer's, cardiovascular disorders, and cancer.Given the rapid growth of the aging population worldwide, understanding these mechanisms is crucial for developing strategies to promote healthier longevity and reduce the socioeconomic burden of age-related diseases.Recent advances in biotechnology and geroscience have identified promising interventions to delay aging and extend lifespan.Emerging therapies, including stem cell treatments and gene-editing technologies and pharmacological interventions such as drugs that inhibit the activity of protein kinases that promote cell senescence.This review examines cellular aging and highlights current strategies, drawn from molecular biology, genetics, and clinical research, that aim to delay aging and promote sustained health and longevity.

Authors

Institutions

Publication Details

Published
2025-09-25
DOI
https://doi.org/10.58445/rars.3104
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Cellular Aging: Mechanisms and Interventions

Weihao Ze
Genetics, Aging, and Longevity in Model Organisms
article

Cellular Aging: Mechanisms and Interventions

Weihao Ze
article en

Abstract

Aging is a complex process that happens in our bodies, especially inside our cells, increasing vulnerability to diseases and death.The importance of studying aging lies in its direct association with major age-related diseases such as Alzheimer's, cardiovascular disorders, and cancer.Given the rapid growth of the aging population worldwide, understanding these mechanisms is crucial for developing strategies to promote healthier longevity and reduce the socioeconomic burden of age-related diseases.Recent advances in biotechnology and geroscience have identified promising interventions to delay aging and extend lifespan.Emerging therapies, including stem cell treatments and gene-editing technologies and pharmacological interventions such as drugs that inhibit the activity of protein kinases that promote cell senescence.This review examines cellular aging and highlights current strategies, drawn from molecular biology, genetics, and clinical research, that aim to delay aging and promote sustained health and longevity.

University Health Care System (US)
Openalex Percentile: Top 77%
Genetics, Aging, and Longevity in Model Organisms
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Cellular Aging: Mechanisms and Interventions — Weihao Ze · (2025) | TGRS Research Map | TGRS