Copper(I)-Anchoring Covalent Organic Polymer for Heterogeneous CuAAC Reaction without Reducing Agents and Copper Leaching
A novel copper-(I)-anchored covalent organic polymer (Cu<sup>+</sup>@COP) is presented as a robust, heterogeneous catalyst for copper-catalyzed azide-alkyne cycloaddition (CuAAC), operating without the need for external reducing agents or observable copper leaching. Cu<sup>+</sup> stabilization is achieved via multidentate N,O-ligand coordination within the polymer matrix, enabling high catalytic efficiency (up to 95% yield) and recyclability. Structural, spectroscopic, and ICP-OES analyses confirm Cu presence, offering an alternative to traditional CuAAC protocols. This system combines operational simplicity, reduced waste, and green chemistry principles, positioning Cu<sup>+</sup>@COP as a practical catalyst for applications in synthetic and materials chemistry.
Authors
- Michele Coluccia (ORCID: https://orcid.org/0000-0002-8703-3635)
- Antonella Fontana (ORCID: https://orcid.org/0000-0002-5391-7520)
- Paolo Guglielmi (ORCID: https://orcid.org/0000-0001-5701-6925)
- Giulia Mazzoccanti (ORCID: https://orcid.org/0000-0001-8655-524X)
- Andrea Giacomo Marrani (ORCID: https://orcid.org/0000-0002-3203-9642)
- Maria Aurora Guarducci (ORCID: https://orcid.org/0000-0002-8820-5523)
- Claudio Villani (ORCID: https://orcid.org/0000-0002-3253-3608)
- Simone Manetto (ORCID: https://orcid.org/0000-0002-5203-6721)
- Alessia Ciogli (ORCID: https://orcid.org/0000-0002-7538-2424)
- Francesco Amato (ORCID: https://orcid.org/0000-0003-1577-7421)
- Serena Pilato (ORCID: https://orcid.org/0000-0003-4971-6483)
Institutions
- University of Chieti-Pescara (IT)
- Sapienza University of Rome (IT)
- Tetra Tech (United States) (US)
Publication Details
- Journal
- ACS Organic & Inorganic Au
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1021/acsorginorgau.5c00067
- Primary Topic
- Covalent Organic Framework Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00