Advances in Fiber Optic Surface-Enhanced Raman Spectroscopy Sensors
Surface-enhanced Raman spectroscopy (SERS) is a highly specific and sensitive analytical technique that identifies molecules by amplifying Raman fingerprints through electromagnetic (EM) and chemical (CM) enhancement mechanisms. When SERS is integrated with microstructured optical fibers, the resulting fiber optic SERS sensors extend the applications for in vivo and in situ analysis. This Review discusses recent advancements in fiber optic SERS sensors. It focuses on the additional Raman signal enhancement achieved through specialty optical fibers, their interaction with SERS active materials, and the corresponding sensing systems. We also highlight the unique advantages, such as enhanced sensitivity, remote sensing capability, and challenges including stability, reproducibility, and background noise. Finally, we discuss the technical development trends, provide an overview of fiber optic SERS sensor applications in liquid-, gas-, and solid-phase analytes, and propose future research directions to overcome current limitations.
Authors
- Junyu Wei
- Minghui Niu (ORCID: https://orcid.org/0009-0005-8298-4561)
- Jinna Chen (ORCID: https://orcid.org/0000-0002-6244-8009)
- Weihao Lin (ORCID: https://orcid.org/0000-0002-1499-2608)
- Liyang Shao (ORCID: https://orcid.org/0000-0003-1272-1959)
- Shuwen Zeng (ORCID: https://orcid.org/0000-0003-2188-7213)
- Perry Ping Shum (ORCID: https://orcid.org/0000-0003-1391-4736)
- Yu Zheng (ORCID: https://orcid.org/0000-0003-3772-5673)
- Chenlong Xue
- Guanghui Wang (ORCID: https://orcid.org/0000-0002-6832-7937)
- Yibin Liu (ORCID: https://orcid.org/0000-0002-3360-5482)
- Yanan Zhang (ORCID: https://orcid.org/0000-0002-3059-9291)
- Jie Hu (ORCID: https://orcid.org/0000-0002-4535-3366)
- Jiaqi Hu (ORCID: https://orcid.org/0000-0002-5770-8048)
- G. Humbert
- Jinqian Lv
Institutions
- Centre National de la Recherche Scientifique (FR)
- Center for NanoScience (DE)
- Southern University of Science and Technology (CN)
- State Key Laboratory on Integrated Optoelectronics (CN)
- XLIM (FR)
- Integrated Optoelectronics (Norway) (NO)
- Ministry of Education (CL)
- Peng Cheng Laboratory (CN)
- Université de Limoges (FR)
- Universidad del Noreste (MX)
- Nanjing University (CN)
- Northeastern University (CN)
Publication Details
- Journal
- ACS Photonics
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1021/acsphotonics.5c00111
- Citations
- 8
- Primary Topic
- Gold and Silver Nanoparticles Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 3.42