Salvianolic acid B and Senkyunolide I synergistically alleviate cardiac hypertrophy and regulate MAP3K1 signaling
These findings underscore GXNT's potent anti-hypertrophic effects, possibly driven by the synergistic actions of Sal B and Sen I, and offer insights into its therapeutic potential through MAP3K1 signaling regulation.
Authors
- Yingchao Wang (ORCID: https://orcid.org/0000-0002-0763-1513)
- Rui Guo (ORCID: https://orcid.org/0000-0002-9329-2668)
- Yue Zhou (ORCID: https://orcid.org/0000-0003-1524-7543)
- Lu Zhao (ORCID: https://orcid.org/0000-0002-2342-3319)
- Li Shao (ORCID: https://orcid.org/0000-0002-3413-7537)
- Miao Zhu (ORCID: https://orcid.org/0000-0001-7295-6384)
- Changtong Liu
Institutions
- Zhejiang Cancer Hospital (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China) (CN)
- Zhejiang Lab (CN)
- Zhejiang Pharmaceutical College (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-09-28
- DOI
- https://doi.org/10.1186/s13020-025-01189-9
- Citations
- 1
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- National Natural Science Foundation of China
- Zhejiang University
- Natural Science Foundation of Zhejiang Province