Current Clinical Features of Diabetic Ketoacidosis in Adults: A German Multicenter Study 2022–2023

The clinical and etiological pattern of DKA is heterogeneous. Patients with pre-existing T1DM showed educational deficits concerning diagnostic and therapeutic measures to prevent DKA. Individuals with recurrent episodes of DKA require individual therapeutic concepts within the multidisciplinary diabetes care team. Emphasizing sick-day-rules in patients being treated with SGLT 2-Is is indispensable to prevent EDKA. Individuals with pre-existing T2DM represent a vulnerable group with severe comorbidities and high mortality risk due to DKA.

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Publication Details

Journal
Diabetes Technology & Therapeutics
Published
2025-09-26
DOI
https://doi.org/10.1177/15209156251380863
Primary Topic
Diabetes and associated disorders
Type
article
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article

Current Clinical Features of Diabetic Ketoacidosis in Adults: A German Multicenter Study 2022–2023

Imke Schamarek, Charlotte T.J. Michels, Marcus Altmeier, A. Holstein et al.
Diabetes Technology & Therapeutics
Diabetes and associated disorders
article

Current Clinical Features of Diabetic Ketoacidosis in Adults: A German Multicenter Study 2022–2023

Imke Schamarek, Charlotte T.J. Michels, Marcus Altmeier, A. Holstein, Dorothea Hinsch, Annekatrin Schwanstecher, Annika Hoyer, David J.F. Holstein, Christoph Terkamp, Clemens Ringel, Jonas A. Linck
article en

Abstract

The clinical and etiological pattern of DKA is heterogeneous. Patients with pre-existing T1DM showed educational deficits concerning diagnostic and therapeutic measures to prevent DKA. Individuals with recurrent episodes of DKA require individual therapeutic concepts within the multidisciplinary diabetes care team. Emphasizing sick-day-rules in patients being treated with SGLT 2-Is is indispensable to prevent EDKA. Individuals with pre-existing T2DM represent a vulnerable group with severe comorbidities and high mortality risk due to DKA.

Diabetes Technology & TherapeuticsVol. 28(3)
Bielefeld University (DE), Medizinische Hochschule Hannover (DE), University Hospital Leipzig (DE), Klinikum Dortmund (DE), Klinikum Lippe (DE), IFB Adiposity Diseases (DE), Agaplesion Diakonieklinikum Rotenburg (DE), Leipzig University (DE)
Openalex Percentile: Top 72%
Diabetes and associated disorders
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Current Clinical Features of Diabetic Ketoacidosis in Adults: A German Multicenter Study 2022–2023 — Imke Schamarek, Charlotte T.J. Michels, et al. · Diabetes Technology & Therapeutics (2025) | TGRS Research Map | TGRS