Chrysanthemum morifolium extract attenuates pathological angiogenesis of age-related macular degeneration via VEGF and Nrf2 pathway modulation
CME exerts dual anti-angiogenic and antioxidant effects in AMD models by simultaneously targeting VEGF-driven angiogenesis and oxidative stress, supporting its therapeutic potential as a safe and effective herbal intervention for neovascular AMD.
Authors
- Jianing Yu (ORCID: https://orcid.org/0000-0001-5425-3271)
- Xiawei Wang (ORCID: https://orcid.org/0009-0007-8324-2070)
- Byron Zhu
- Feng Zhu (ORCID: https://orcid.org/0000-0003-1172-0102)
- Jiangning Hu (ORCID: https://orcid.org/0000-0002-2076-4505)
- Gu Lei
- Xiaorong Wang (ORCID: https://orcid.org/0000-0001-7065-8615)
- Ming‐Wei Lin (ORCID: https://orcid.org/0000-0003-2026-7178)
- Tiantian Cheng (ORCID: https://orcid.org/0000-0002-3734-0290)
- H. Pan
- G. -J. Jiang
Institutions
- Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China) (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.jep.2025.120660
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71