TCEB2 promotes M2 polarization of macrophages in triple negative breast cancer by mediating ubiquitination degradation of Slit2 through recruiting NEDD4
TCEB2 upregulation promoted TNBC-induced M2 macrophage polarization to accelerate TNBC development by mediating Slit2 K63-ubiquitination degradation through interacting with NEDD4.
Authors
- Jie Zeng (ORCID: https://orcid.org/0009-0003-0829-973X)
- Jianing Yi (ORCID: https://orcid.org/0000-0002-3282-3285)
- Haoli Gong
- Xiao Wang (ORCID: https://orcid.org/0000-0002-0077-7341)
- Liu Li (ORCID: https://orcid.org/0000-0002-9746-0067)
- Luyao Liu (ORCID: https://orcid.org/0000-0001-5241-967X)
Institutions
- Central South University (CN)
- Hunan Normal University (CN)
- Hunan Provincial People's Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.tranon.2025.102536
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00