Systematic evaluation of genetic polymorphisms in carcinogen metabolizing enzymes associated with the risk of oral potentially malignant disorders occurrence
This analysis for the first time investigated SNPs in carcinogen metabolizing enzymes with OPMD, suggesting that polymorphisms in CYP2E1 PstI, GSTM1, GSTM3 and GSTT1 play roles in OPMD occurrence and highlighting their potential in risk stratification and early detection strategies.
Authors
- Chao Lou
- Linjun Shi (ORCID: https://orcid.org/0000-0002-9351-8364)
- Wei Liu (ORCID: https://orcid.org/0000-0003-0948-7807)
- Yuhan Zhu (ORCID: https://orcid.org/0000-0002-7817-820X)
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- Journal of Dental Sciences
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.jds.2025.09.010
- Citations
- 1
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47