Dementia risk prediction in the general population: external validation of a prediction model in the population-based LifeLines Cohort Study

In this study the basic dementia risk prediction model overestimated the risk of dementia, but had reasonable discriminative ability in the Lifelines cohort. Within this validation cohort the potential of the model is underestimated due to low incidence of reported dementia. Further validation is required to determine the true value of the model. Studies assessing its implementation feasibility in primary care should also be conducted.