Effectiveness and safety of algorithm for treating pregnant women with syphilis and history of immediate allergy to penicillin
Our algorithm for managing immediate reactions to penicillin is effective and safe. Skin testing identifies patients at higher risk for reactions. This study enables the identification of pregnant women with a history of high risk for immediate hypersensitivity to penicillin, allowing for safe desensitization treatment, or can offer low-risk pregnant women the option to delabel the allergy through a provocation test.
Authors
- Juliana Fóes Bianchini Garcia (ORCID: https://orcid.org/0000-0002-6372-5012)
- Marcelo Vívolo Aun (ORCID: https://orcid.org/0000-0001-9882-5200)
- Jorge Kalil (ORCID: https://orcid.org/0000-0001-8415-4274)
- Bruna Gehlen
- Pedro Francisco Giavina-Bianchi Junior (ORCID: https://orcid.org/0000-0002-1034-7580)
- André Luiz Oliveira Feodrippe (ORCID: https://orcid.org/0009-0007-6440-1267)
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.jacig.2025.100572
- Citations
- 1
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.16