Total intravenous sedation with target-controlled infusion in dentistry: clinical experience with the third-generation Eleveld pharmacokinetic/pharmacodynamic model
TCI-based moderate sedation using the Eleveld model for propofol and remifentanil is safe, effective, and well-tolerated in dental settings. The model offers predictable sedation depth, rapid recovery, and high levels of patient satisfaction, supporting its broader implementation in the management of dental anxiety.
Authors
- Douglas Lobb (ORCID: https://orcid.org/0000-0002-8034-4836)
- Don Macalister (ORCID: https://orcid.org/0000-0002-0297-754X)
- Masoud MiriMoghaddam (ORCID: https://orcid.org/0000-0002-2631-6156)
- R. Bedi
- Hollis Lai (ORCID: https://orcid.org/0000-0002-5531-6622)
- Keith Anderson (ORCID: https://orcid.org/0009-0005-7963-822X)
Institutions
- University of Auckland (NZ)
- University of Alberta (CA)
- University of Calgary (CA)
- Foothills Medical Centre (CA)
- New Zealand Brain Research Institute (NZ)
- Christchurch Clinical Studies Trust (NZ)
Publication Details
- Journal
- Journal of Dental Anesthesia and Pain Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.17245/jdapm.2025.25.5.313
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00