Cold-season programming reinforces the brown fat–cardiometabolic health link
Recent work by Yoneshiro et al. links brown adipose tissue (BAT) activity to environmental temperatures during conception, highlighting intergenerational influences shaping BAT function. Here we explore how these findings translate into a cardiometabolic health phenotype and discuss how it can be mediated through sperm epigenetic programming.
Authors
- Taylah L. Gaynor (ORCID: https://orcid.org/0000-0001-5774-6442)
- Camilla Schéele (ORCID: https://orcid.org/0000-0002-6055-9709)
Institutions
- University of Copenhagen (DK)
- Novo Nordisk Foundation (DK)
Publication Details
- Journal
- Trends in Endocrinology and Metabolism
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.tem.2025.09.007
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Novo Nordisk
- Novo Nordisk Fonden
- Novo Nordisk Foundation Center for Basic Metabolic Research