Ten-Day-Old Neonate Cocaine Exposure and Human Milk: A Case Report
Case reports of lactational intoxications are frequent, especially with drugs, like COC, which can build up in acidic body fluids, like human milk, without the ability to disperse. Development of new biomarkers for early diagnosis of intoxication are needed for substances with toxic potential, such as COC. An increase in activated Partial Thromboplastin Time (aTTP) time may be associated with lactational COC intoxication and may serve as an early biomarker for liver damage. Furthermore, immunochromatography assays serve as alternative screening tools, particularly well-suited for emergency scenarios involving suspected drug exposure, employing biological samples to enable rapid assessment. More studies are needed to assess the influence of COC exposure on coagulation parameters.
Authors
- Leonardo Corrêa Cardoso (ORCID: https://orcid.org/0000-0002-5121-707X)
- André Valle de Bairros (ORCID: https://orcid.org/0000-0002-8393-1972)
- Karla Nunes Pereira
- Nathalie Michels (ORCID: https://orcid.org/0000-0002-3069-7254)
- Fernanda Ziegler Reginato (ORCID: https://orcid.org/0000-0001-8076-0912)
- Karol Andriely de Vargas Paier (ORCID: https://orcid.org/0009-0004-3495-8425)
- Ana Carolina Kieling
Institutions
- Universidade Federal de Santa Maria (BR)
- Hospital Universitário de Santa Maria (BR)
Publication Details
- Journal
- Journal of Human Lactation
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1177/08903344251373052
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00