Cyanoacrylate Glue Ablation of Perforating Veins in Patients with Recurrent Varicose Veins of the Lower Extremities: A Prospective Study

Objective. To evaluate the short-term outcomes of original cyanoacrylate glue ablation technique for incompetent perforating veins. Material and methods. A prospective cohort study enrolled 209 patients (253 limbs) with recurrent varicose veins. All of them underwent cyanoacrylate glue ablation of incompetent veins. The follow-up was 6 months. Incidence of perforating vein ablation (no blood flow according to ultrasound data) was assessed. No migration of cyanoacrylate glue into deep venous system was a safety criterion. Results. In each patient, 1—4 perforating veins were obliterated (331 veins in total). Diameter of perforating veins varied from 2.5 to 7.4 mm (mean 4.2 mm). About 0.4 ml of cyanoacrylate glue was used per a procedure. Total occlusion of perforating veins was achieved in 245 lower extremities after 24 hours. Blood flow through the perforating was partially preserved in 5 lower extremities. Excellent technical results were achieved 2 months after procedure in 241 (95%) lower extremities, after 6 months — in 238 (94%) extremities. Glue migration into deep veins occurred in 3 cases. Conclusions. In most cases, original technique of cyanoacrylate obliteration of perforating veins provides excellent technical results with minimal risk of complications.