A Multifunctional β‐CD@Menthol/GGP@CNC Composite Hydrogel with Enhanced Mechanical Strength and Antioxidant/Antibacterial Properties

Abstract This study reports a composite hydrogel composed of ginseng peptides (GGP), cellulose nanocrystals (CNC), and menthol@β‐cyclodextrin (β‐CD@Menthol). Characterization confirms the successful inclusion of menthol, enhances crystallinity, and a uniform porous structure. The β‐CD@Menthol/GGP@CNC hydrogel exhibits high mechanical strength (elongation 1495.4%, toughness 3320.0 kJ m −3 ), strong antioxidant activity (ABTS scavenging 90.9%), excellent swelling capacity (1198.3% in saline), and effective antibacterial effects against Escherichia coli and Staphylococcus aureus . These properties highlight its promise as a multifunctional wound dressing to combat infection and oxidative stress in chronic wounds.

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Publication Details

Journal
Crystal Research and Technology
Published
2025-09-27
DOI
https://doi.org/10.1002/crat.70041
Primary Topic
Hydrogels: synthesis, properties, applications
Type
article
Field-Weighted Citation Impact
0.00

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article

A Multifunctional β‐CD@Menthol/GGP@CNC Composite Hydrogel with Enhanced Mechanical Strength and Antioxidant/Antibacterial Properties

Linli Gan, Shilei Zhang, Hao Shi, Wancheng Song
Crystal Research and Technology
Hydrogels: synthesis, properties, applications
article

A Multifunctional β‐CD@Menthol/GGP@CNC Composite Hydrogel with Enhanced Mechanical Strength and Antioxidant/Antibacterial Properties

Linli Gan, Shilei Zhang, Hao Shi, Wancheng Song
article en

Abstract

Abstract This study reports a composite hydrogel composed of ginseng peptides (GGP), cellulose nanocrystals (CNC), and menthol@β‐cyclodextrin (β‐CD@Menthol). Characterization confirms the successful inclusion of menthol, enhances crystallinity, and a uniform porous structure. The β‐CD@Menthol/GGP@CNC hydrogel exhibits high mechanical strength (elongation 1495.4%, toughness 3320.0 kJ m −3 ), strong antioxidant activity (ABTS scavenging 90.9%), excellent swelling capacity (1198.3% in saline), and effective antibacterial effects against Escherichia coli and Staphylococcus aureus . These properties highlight its promise as a multifunctional wound dressing to combat infection and oxidative stress in chronic wounds.

Crystal Research and TechnologyVol. 60(11)
Xinjiang Medical University (CN), Huaiyin Institute of Technology (CN)
Huaiyin Institute of Technology
Openalex Percentile: Top 79%
Hydrogels: synthesis, properties, applications
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A Multifunctional β‐CD@Menthol/GGP@CNC Composite Hydrogel with Enhanced Mechanical Strength and Antioxidant/Antibacterial Properties — Linli Gan, Shilei Zhang, et al. · Crystal Research and Technology (2025) | TGRS Research Map | TGRS