Chondroitin sulfate and hyaluronan in the vitreous of patients with rhegmatogenous retinal detachment
The significant degree of non-sulfated CS domains and decreased HA concentrations in the vitreous of RRD patients could weaken structural organization of the vitreous. Reduced vitreous stability can cause pathological vitreoretinal traction, ultimately leading to rhegmatogenous retinal detachment.
Authors
- Willeke F. Daamen (ORCID: https://orcid.org/0000-0003-3155-3030)
- B. Jeroen Klevering (ORCID: https://orcid.org/0000-0002-3062-6544)
- Arie Oosterhof
- Elly M. M. Versteeg (ORCID: https://orcid.org/0000-0001-7047-5173)
- Anneke I. den Hollander (ORCID: https://orcid.org/0000-0003-0634-5408)
- S. Keijser
- Björn Bakker (ORCID: https://orcid.org/0000-0003-3095-7287)
- Birgit Marlies Govers (ORCID: https://orcid.org/0000-0003-2602-3924)
- Toin H. Van Kuppevelt (ORCID: https://orcid.org/0000-0002-7028-6783)
- Magdalena J de Bruijne
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- Experimental Eye Research
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.exer.2025.110672
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stichting Steunfonds Uitzicht
- Oogfonds
- Landelijke Stichting voor Blinden en Slechtzienden
- Stichting voor Ooglijders