A Rare Nasopharyngeal Hemangioma Presenting as Recurrent Cyanotic Apnea in a Neonate: A Case Report and Literature Review
<b>Background:</b> Infantile hemangiomas (IHs) are the most common vascular tumors of infancy, but airway involvement is rare and potentially life-threatening. While subglottic and laryngeal regions are most frequently affected, nasopharyngeal hemangiomas are exceptionally uncommon, particularly in premature infants presenting with nonspecific symptoms such as apnea and cyanosis. <b>Case Presentation:</b> We describe a female infant born prematurely at 35 weeks via cesarean section, who developed recurrent apnea and cyanotic episodes shortly after discharge. Flexible bronchoscopy revealed a nasopharyngeal mass causing upper airway obstruction, and imaging raised suspicion of a hemangioma. The patient underwent surgical excision of the lesion and was started on a tapering course of prednisolone. Postoperative recovery was favorable, and oral propranolol was initiated to prevent recurrence. At follow-up, the patient demonstrated normal development without respiratory symptoms. <b>Conclusion:</b> Nasopharyngeal hemangiomas are rare and may present subtly in premature infants. Early bronchoscopy and imaging should be considered in cases of unexplained apnea or airway compromise. A multidisciplinary approach ensures timely diagnosis and effective treatment, minimizing long-term respiratory complications.
Authors
- Aslan Ahmadi
- Pershia Davoodi Karsalari (ORCID: https://orcid.org/0009-0007-3706-2618)
- Noosha Samieefar (ORCID: https://orcid.org/0000-0001-6429-7729)
- Parinaz Alizadeh
- Samin Mortaheb (ORCID: https://orcid.org/0009-0000-8190-6282)
- Heliya Rafsanjani (ORCID: https://orcid.org/0009-0007-2236-0030)
Institutions
- Iran University of Medical Sciences (IR)
- Universal Scientific Education and Research Network (IR)
- Children's Medical Center (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Case Reports in Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/carm/7094069
- Primary Topic
- Vascular Malformations and Hemangiomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00