Gray matter microstructural abnormalities in temporal lobe epilepsy with hippocampal sclerosis and MRI negative
TLE-HS patients show extensive GM microstructural changes, primarily in the frontotemporal lobe and limbic system. Our findings support the hypothesis that TLE-HS and MRI-negative TLE represent two distinct pathological entities. This study provides strong evidence of the pattern of microstructural alterations in TLE and offers insights into the understanding of GM microstructural changes in TLE patients.
Authors
- Wenrui Yang (ORCID: https://orcid.org/0000-0001-9650-3937)
- Jian Li (ORCID: https://orcid.org/0000-0002-2623-4943)
- Jiandong Niu (ORCID: https://orcid.org/0000-0002-9425-5164)
- Xiaolin Wang (ORCID: https://orcid.org/0000-0001-9510-4045)
- Zhuo Wang (ORCID: https://orcid.org/0000-0002-7076-8432)
- Yuhui Xiong
- Dawei Song
- Bing Chen (ORCID: https://orcid.org/0000-0002-7867-756X)
Institutions
- General Electric (Spain) (ES)
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- European Journal of Radiology
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.ejrad.2025.112455
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00