Proteomic and Metabolomic Interplay in the Regulation of Energy Metabolism During Obesity and Metabolic Syndrome
Our data suggested an interplay between anti-inflammatory (DMBT1, 3-hydroxybutyrate, 5-oxoproline) and pro-inflammatory pathways (Vanin-1, α-tocopherol, PTPRJ) during disorders of obesity and MetS, demonstrating the potential of an integrated multi-omics approach for a better understanding of the mechanism behind obesity-associated metabolic diseases.
Authors
- Youssef Bacila Sade (ORCID: https://orcid.org/0000-0001-6041-0288)
- Fabiano Lopes Thompson (ORCID: https://orcid.org/0000-0002-7562-1683)
- Carlos Vinícius Ferreira da Silva (ORCID: https://orcid.org/0000-0003-3301-2406)
- Cristiane Thompson
- Thaís Regiani Cataldi (ORCID: https://orcid.org/0000-0002-9827-2017)
- Carlos José Ferreira da Silva
- Carlos Alberto Labate (ORCID: https://orcid.org/0000-0001-7309-1300)
- Sandra Mara Naressi Scapin (ORCID: https://orcid.org/0000-0002-5405-7219)
- Carina Maciel da Silva‐Boghossian
- Eidy de Oliveira Santos (ORCID: https://orcid.org/0000-0002-4385-6066)
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade de São Paulo (BR)
- Universidade Unigranrio (BR)
- Universidade do Estado do Rio de Janeiro (BR)
- Instituto Nacional de Metrologia, Qualidade e Tecnologia (BR)
Publication Details
- Journal
- Diabetes/Metabolism Research and Reviews
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1002/dmrr.70090
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- National Institute of Metrology, China