Abnormal Platelet-to-Lymphocyte Ratio is Associated with Poor Outcomes in Pediatric Sepsis

High PLR at admission was independently associated with worse clinical outcomes in pediatric patients with sepsis. Adding PLR to the Pediatric Index of Mortality and Pediatric Risk of Mortality-III enhanced the predictive performance. PLR is a simple and readily available index that may improve early risk stratification in this high-risk population.

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Publication Details

Journal
Shock
Published
2025-09-09
DOI
https://doi.org/10.1097/shk.0000000000002681
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Abnormal Platelet-to-Lymphocyte Ratio is Associated with Poor Outcomes in Pediatric Sepsis

Christian Gerges, Daniel T. Cater, Courtney Marie Rowan, Francis Pike
Shock
Inflammatory Biomarkers in Disease Prognosis
article

Abnormal Platelet-to-Lymphocyte Ratio is Associated with Poor Outcomes in Pediatric Sepsis

Christian Gerges, Daniel T. Cater, Courtney Marie Rowan, Francis Pike
article en

Abstract

High PLR at admission was independently associated with worse clinical outcomes in pediatric patients with sepsis. Adding PLR to the Pediatric Index of Mortality and Pediatric Risk of Mortality-III enhanced the predictive performance. PLR is a simple and readily available index that may improve early risk stratification in this high-risk population.

ShockVol. 65(1)
Riley Hospital for Children (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 64%
Inflammatory Biomarkers in Disease Prognosis
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